Effect of Vitamin A Supplements with Iron Therapy among Adolescent Girls

Authors

  • Patel SK, Chaturvedi A, Bhardwaj A, Chandra S, Naik G, Sharma HB

DOI:

https://doi.org/10.37506/ijop.v7i3.117

Keywords:

Iron deficiency anaemia, Vitamin A, Haemoglobin, Adolescence.

Abstract

Background

Despite of extensive management programmes for iron deficiency anaemia, it remains a challenge for healthcare professionals. So, there is a requirement of supplementing the conventional therapy with some micronutrients which have a possible role in combating the problems of anaemia. Vitamin A is one of those possible micronutrients.

Material and Method

Adolescent girl students from a school who were diagnosed as anaemia were categorised randomly into two interventional groups. Those who were not diagnosed as anaemia formed the third group. In group A, Vitamin A supplementation (2, 00, 000 IU single dose) along with Iron in the form of FeSO4 was given for 100 days. Group B students received only Iron supplementation for the same period. Only placebo was given to the students of group C.

Results

In group A the mean value for blood haemoglobin improved from 10.128+0.196 gm/dL to 12.216+0.215 gm/dL. The improvement was extremely significant (p<0.0001). In group B mean value for blood haemoglobin improved from 10.141+0.210 gm/dL to 11.766+0.218 gm/dL and was very significant (p<0.0001). In group C, the mean value for blood haemoglobin was 12.809+0.099, which significantly improved to 13.018+0.119 gm/dL. (p=0.008). The %age change over baseline was more in group A (20.39%) than group B (12.38%) as compared to group C (2.77%).

Conclusion

This study concluded that vitamin A supplementation helps to restore the blood haemoglobin level along with iron therapy and helps to improve the status of anaemia. Further studies involving large population are required to establish the definitive role of vitamin A supplementation in anaemia and to recommend it as a standard additive therapeutic agent.

Author Biography

Patel SK, Chaturvedi A, Bhardwaj A, Chandra S, Naik G, Sharma HB

Patel SK1, Chaturvedi A2,*, Bhardwaj A3, Chandra S4, Naik G5, Sharma HB6

1Assistant Professor, Department of Physiology, Raipur Institute of Medical Science, Raipur, Chhattisgarh

2Associate Professor, Department of Physiology, Govt Medical College, Badaun, Uttar Pradesh

3Associate Professor, Department of Physiology, Sarojini Naidu Medical College, Agra, U.P.

4Lecturer, Department of Physiology, Sarojini Naidu Medical College, Agra, U.P.

5Senior Resident, Department of Community and Family Medicine, All India Institute of Medical Sciences, Raipur

6Senior Resident, Department of Physiology, All India Institute of Medical Sciences, New Delhi

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Published

2019-07-25

How to Cite

Patel SK, Chaturvedi A, Bhardwaj A, Chandra S, Naik G, Sharma HB. (2019). Effect of Vitamin A Supplements with Iron Therapy among Adolescent Girls. International Journal of Physiology, 7(3), 45–51. https://doi.org/10.37506/ijop.v7i3.117