Assessment of Sympathetic Activity Using Hand Grip Test in Obese Type 2 Diabetes Mellitus Patients
Keywords:Hand grip test, sympathetic activity, Obese, Type 2 diabetes mellitus.
The aim of the study is to assess sympathetic activity in Obese type 2 Diabetes mellitus patients
To investigate any changes in sympathetic activity in obese type 2 diabetes mellitus patients using hand grip test
50 subjects of both the genders with type 2 Diabetes mellitus of 10–15 years duration and BMI > 25kg/m2 were selected as study group. In sitting posture the subject was asked to apply pressure on hand grip dynamometer at 30% of maximum voluntary contraction (MVC) for 1 minute. BP was recorded simultaneously from non-exercising arm. The procedure was repeated thrice with 5 minutes interval in between. The average increase in DBP was noted as the test response and comparison was made with readings of hand grip test from nonobese nondiabetic subjects which were selected as control group.
Statistical analysis was done using unpaired t test. Increase in diastolic blood pressure with handgrip test in study group was significantly reduced compared to control group.
Sympathetic neuropathy is seen in obese diabetic patients. Obesity could be involved in the impairment of CAN function in type 2 diabetics and body weight control could provide an approach to reducing neuropathic complications.
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