Forced Vital Capacity Parameters in Tibetan Youths Born and Residing in India
DOI:
https://doi.org/10.37506/ijop.v7i3.175Keywords:
Tibetan males with Indian origin, Indian males, pulmonary function, environmental factors.Abstract
Background and Objective
There is evidence of considerable variation in pulmonary functions in different ethnic groups, between races and across generations attributed to genetic factors leading to the formation of airways of different size or with different elastic recoil. This study was aimed to evaluate and compare pulmonary functions between Tibetan males with Indian origin and young Indian males.
Materials and Method
Forced Vital Capacity parameters (measured using spiroanalyser SPL-95) of 50 Tibetan males aged 20–30 years born and brought up in Mundgod, North Karnataka District, were compared with 50 Indian males matched for age, sex, height and weight as controls. The obtained data was analyzed between the two groups by applying unpaired student's ‘t’ test.
Results
The anthropometric data between the two groups showed no statistical significant difference. The FVC (litres), FEV1(L/sec) and FEV1/FVC were higher in Tibetan males with Indian origin when compared to Indian males being statistically significant at P<0.001 [95% CI(0.79, 1.08), (0.87, 1.20) and (0.02, 0.06) respectively]. Flow rates [MMEF (L/sec), MEF75% (L/sec) and MEF50% (L/sec)] were higher in Tibetan males as compared to Indian males. MMEF was statistically significant at P <0.01[95% CI (0.24, 1.17)], MEF75% and MEF50% were statistically significant at P <0.001 [95%CI (2.13, 3.73) and (0.43, 1.51) respectively]. The MEF25% was lesser in Tibetan males than compared to Indian males but was not statistically significant.
Conclusion
There is a difference in lung functions between Tibetan youths with Indian origin and Indian youths though both share similar environmental challenges showing that Tibetan males with Indian origin still retain better respiratory parameters as their ancestors which could be due to their inheritance of genetic factors that favour their survival at a high altitude
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