Histological and Biometric Study of the Effects of Fusarium Graminarum Silver Nanoparticles on the Kidney in Male Albino Mice

Abstract

An approach to synthesizing silver nanoparticles(AgNPs)using a Fusarium graminarum fungus was

established in the present study.These nanoparticles are identified with the following techniques to confirm

the form, size, and other physical properties of the crystal:UV-Visible Spectroscopy(UV-Vis),where the

AgNPs showed absorbance at 420 nm, while X-Ray Diffraction (XRD)showed diffraction peaks at(38.05°,4

nm).The experiment consisted of 40 mice divided into two groups, the first group of 20 mice was considered

to be the control animals and the other group 20mice was 21day of treatment with a dose of AgNPs(0.1ml/

day).Microscopic examination of the kidney section showed lobulated glomeruli,a large area of hemorrhage,

changes in degeneration, and inflammatory cell infiltration. Biometric changes of the renal corpuscle showed

no significant difference between the study group,while Bowman’s capsule,Proximal,and distal convoluted

tubules revealed increased significant differences between the two groups.