Molecular Detection of blaOXA-51 in Carbapenem-resistant Acinetobacterbaumannii Isolated from Different Clinical Sources

Abstract

Carbapenems are the drugs of choice against serious infections caused by Gram-negative bacteria
Carbapenem-resistant. Acinetobacterbaumannii (CRAB) represents one of the important causing agents
of nosocomial infections especially in immunocompromised and Intensive Care Units (ICUs) patients. The
aim of this work was to identify the Carbapenem-Resistant genes in Acinetobacterbaumannii isolated from
Baghdad and Ramadi hospitals. Among 48A. baumannii isolates, 33 isolates (68.75%) were resistant to
imipenem and meropenem. One gene for carbapenem resistance (blaOXA-51 like) were amplified by PCR.
The presence of blaOXA-51-like genes in 100% of CRAB isolates indicated that the blaOXA-51-like genes
are the predominant mechanism for imipenem resistance in our isolates.