Comparison of Average Inhibition Zones of Methanolic Extracts of Chaetomium globosum on the Growth of Different Groups of Pathogenic Micro-Organisms

Abstract

The objectives of this study were analysis of the secondary metabolite products and evaluation of antibacterial activity. The FTIR analysis of Chaetomium globosum proved the presence of functional group
assignment Alkyl halides, Amide, and Alkane with Peak (Wave number cm-?) 1018.41 (Strong), 1238.30
(Strong), 1317.38 (Strong), 1379.10 (Strong), 1614.42 (Bending), 2850.79 (Strong), 2920.23 (Strong). Zone
of inhibition (mm) of test bacterial strains to Chaetomium globosum bioactive compounds and standard
antibiotics were (4.00±0.31), (4.77±0.13), (5.00±0.16), (3.22±0.41), and (4.29±0.11) uses Chaetomium
globosum bioactive compounds, and (2.01±0.10), (1.77±0.41), (1.98±0.11), (2.00±0.30), and (1.05±0.42)
uses Rifambin, and (2.42±0.18), (2.12±0.46), (1.40±0.12), (1.00±0.10), and (2.90±0.47) uses Kanamycin
for Staphylococcus aureus, Escherichia coli, Proteus mirabilis, Klebsiella pneumonia, Pseudomonas
eurogenosa respectively. Chaetomium globosum was very highly active against Escherichia coli (4.77±0.13).