Prediction Accuracy of Irisplex Tool in Different Population

Abstract

Forensic DNA phenotyping is a rapidly advancing field that seeks to predict an individual’s physical appearance
from their DNA profile. The ability to infer phenotypic traits, such as eye colour, hair colour, skin colour, and facial
features from DNA evidence holds significant potential for criminal investigations especially when traditional
investigative methods such as DNA profiling yield limited results. Forensic DNA Phenotyping (FDP) has now
become one of the beneficial methods which aids in police investigation to narrow down the investigative
procedure in various types of forensic cases such as identification of unknown in mass disaster case or unknown
perpetrator who cannot be identified by the help of forensic STR- profiling. Benefits of FDP is that it has overcome
to limitations that exist with conventional methods of human identification as it can predict individual’s externally
visible characteristics (EVCs) from DNA as well as it is more focused on obtaining genetic profiles from crime
scene samples not harming dignity or integrity rights of individual. Phenotype of individual can be identified by
help of Tools which can predict physical characteristics of individual. IrisPlex is the first tool which predict Eye
colour, HIrisPlex is the tool which can predict both eye colour and Hair colour whereas HIrisPlex-S can predict
skin colour, hair colour as well as eye colour so, Forensic DNA Phenotype has benefits over other traditional
methods and can help law enforcement to solve criminal as soon as possible.