Antibody Detection (IgG, IgM) of both HSV-1 and VZV in Serum and Saliva of Bell’s Palsy Patients Recovered by Low Level Laser Therapy

Abstract

Bell’s palsy (BP) is the commonest form of facial palsy. It often starts with pain behind the ear, with impairment of taste sensation. One-hundred and twenty (120) subjects were participated in this study; they were divided into two groups: Group one: Eighty (80) Bell’s palsy patients included in this study. These patients were treated by LLLT. Diagnosis of patients with Bell’s palsy based on House- Brachmann Scale (HBS, 1996); this diagnosis was done by neuromedicine / neurosurgery specialists, and group two: Forty (40) healthy control subjects (volunteers) with no signs and symptoms of any systemic diseases, with matched ages and genders with BP patients. There was a highly significant reduction in serum HSV-1 IgG level after LLLT (p<0.001). No significant differences were observed before and after LLLT regarding salivary HSV-1 IgG level, serum HSV-1 IgM level and salivary HSV-1 IgM level. A highly significant decline in serum VZV IgG level was observed after LLLT (p<0.001). No significant differences were observed before and after LLLT regarding salivary VZV IgG level, serum VZV IgM level and salivary VZV IgM level.